Forced entry into the nucleus
Nature Cell Biology (IF28.213), Pub Date : 2022-06-09, DOI: 10.1038/s41556-022-00939-3
Stefan Petrovic, André Hoelz
The nuclear pore complex (NPC) regulates transport of macromolecules into and out of the nucleus. A study now shows that mechanical force applied on the nucleus affects the transport rates across the NPC diffusion barrier, modulating the nuclear localization of certain cargos.
Nature Cell Biology (IF28.213), Pub Date : 2022-06-09, DOI: 10.1038/s41556-022-00939-3
Stefan Petrovic, André Hoelz
The nuclear pore complex (NPC) regulates transport of macromolecules into and out of the nucleus. A study now shows that mechanical force applied on the nucleus affects the transport rates across the NPC diffusion barrier, modulating the nuclear localization of certain cargos.
