This work provides a practical engineering design on the new 600 MWe coal-fired power plant coupled with CaO-based carbon capture system. Three heating surface layout cases are proposed in order to realize the high temperature heat source of the new power plant to heat the feed water into the superheated steam (24.2 MPa, 566 °C). In addition, pipeline calculation and economic analysis for three cases are carried out. The results show that the heat exchange area of three cases increases, respectively by around 33.5%, 47.3% and 53.7% as comparing to the benchmark 600 MWe coal-fired power plant under the carbon capture efficiency of the coupled system is around 90%. In the pipeline design, the flue gas resistance of case 1 through heat exchange pipeline is about 0.74 MPa. The economic analysis shows that case 1 has a slight advantage as comparing to cases 2 and 3. The research provides a good direction for future research direction of the coal-fired power plant coupled with CaO-based carbon capture system.