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What Are the Minimally Important Changes of Four Commonly Used Patient-Reported Outcome Measures for 36 Hand and Wrist Condition-Treatment Combinations?
Clinical Orthopaedics and Related Research  (IF4.176),  Pub Date : 2021-12-27, DOI: 10.1097/corr.0000000000002094
Lisa Hoogendam, Jaimy Emerentiana Koopman, Yara Eline van Kooij, Reinier Feitz, Caroline Anna Hundepool, Chao Zhou, Harm Pieter Slijper, Ruud Willem Selles, Robbert Maarten Wouters

Patient-reported outcome measures (PROMs) are frequently used to assess treatment outcomes for hand and wrist conditions. To adequately interpret these outcomes, it is important to determine whether a statistically significant change is also clinically relevant. For this purpose, the minimally important change (MIC) was developed, representing the minimal within-person change in outcome that patients perceive as a beneficial treatment effect. Prior studies demonstrated substantial differences in MICs between condition-treatment combinations, suggesting that MICs are context-specific and cannot be reliably generalized. Hence, a study providing MICs for a wide diversity of condition-treatment combinations for hand and wrist conditions will contribute to more accurate treatment evaluations.