Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations Journal of Cachexia, Sarcopenia and Muscle (IF12.91), Pub Date : 2021-10-20, DOI: 10.1002/jcsm.12766 Claire Laurens, Franziska Grundler, Anthony Damiot, Isabelle Chery, Anne-Laure Le Maho, Alexandre Zahariev, Yvon Le Maho, Audrey Bergouignan, Guillemette Gauquelin-Koch, Chantal Simon, Stéphane Blanc, Françoise Wilhelmi de Toledo
Fasting is attracting an increasing interest as a potential strategy for managing diseases, including metabolic disorders and complementary cancer therapy. Despite concerns of clinicians regarding protein catabolism and muscle loss, evidence-based clinical data in response to long-term fasting in healthy humans are scarce. The objective of this study was to measure clinical constants, metabolic, and muscular response in healthy men during and after a 10 day fast combined with a physical activity programme.