Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Skeletal muscle atrophy-induced hemopexin accelerates onset of cognitive impairment in Alzheimer's disease Journal of Cachexia, Sarcopenia and Muscle (IF12.91), Pub Date : 2021-10-17, DOI: 10.1002/jcsm.12830 Tsukasa Nagase, Chihiro Tohda
Alzheimer's disease (AD) is an unmet medical need worldwide, and physical inactivity is a risk factor for AD. Performing physical exercise is difficult at old age, and thus, decline in physical movement may be a cause of age-associated lowering of the brain function. This study aimed to elucidate the molecular mechanism and onset of the skeletal muscle atrophy-induced acceleration of AD.