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Ca2+ kickstarts antiviral RNAi
Cell Host & Microbe  (IF21.023),  Pub Date : 2021-09-08, DOI: 10.1016/j.chom.2021.08.008
April DeMell, Savithramma P. Dinesh-Kumar

RNAi is a major plant antiviral strategy. However, the mechanisms triggering RNAi are unknown. In this issue of Cell Host & Microbe, Wang et al. (2021) demonstrate that wound-induced calcium signaling induces RNAi activation. As a counter-defense, a viral suppressor of RNAi (VSR) interferes with players in calcium signaling.