Find Paper, Faster
Example:10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Diagnosis of tuberculous pleural effusions: A review
Respiratory Medicine  (IF3.415),  Pub Date : 2021-09-06, DOI: 10.1016/j.rmed.2021.106607
Christian M. Lo Cascio, Viren Kaul, Sahajal Dhooria, Abhinav Agrawal, Udit Chaddha

Tuberculous pleural effusion (TPE) is the second most common presentation of extrapulmonary tuberculosis. The paucibacillary nature of the effusion poses diagnostic challenges. Biomarkers like adenosine deaminase and interferon-γ have some utility for diagnosing TPEs, as do cartridge-based polymerase chain reaction (PCR) methods. When these fluid studies remain indeterminate, pleural biopsies must be performed to confirm the diagnosis. This review article elaborates on the scientific evidence available for various diagnostic tests and presents a practical approach to the diagnosis of TPEs.