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TIM4+ adipose tissue-resident macrophages: new modulators of adiposity
Nature Reviews Endocrinology  (IF43.33),  Pub Date : 2021-08-19, DOI: 10.1038/s41574-021-00554-6
Huh, Jin Young, Kim, Jae Bum

Adipose tissue macrophages (ATMs) have important roles in the regulation of inflammatory responses and insulin resistance in obesity. A new study reports that a subpopulation of ATMs, TIM4+ resident ATMs, modulate adipocyte size via platelet-derived growth factor-CC production during development and diet-induced adipose tissue expansion.