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A renal and hepatic toxicity analysis of remdesivir formulations: Does what is on the inside really count?
Antimicrobial Agents and Chemotherapy  (IF5.191),  Pub Date : 2021-07-26, DOI: 10.1128/aac.01045-21
Sunish Shah, Tyler W. Ackley, Jeffrey E. Topal

It has been postulated that the injectable solution formulation of remdesivir could be more nephrotoxic than the lyophilized powder since it contains twice as much sulfobutylether-β-cyclodextrin (SBECD). Therefore, we evaluated 1000 hospitalized patients ...