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Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola
Antimicrobial Agents and Chemotherapy  (IF5.191),  Pub Date : 2021-07-12, DOI: 10.1128/aac.01117-21
Victoria C. Yan, Florian L. Muller

Remdesivir is a nucleoside monophosphoramidate prodrug that has been FDA-approved for COVID-19. However, the clinical efficacy of remdesivir for COVID-19 remains contentious, as several trials have not found statistically significant differences in either ...