Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Development of a High Resolution Melting Curve Analysis for the Detection of Hemoglobin δ-Chain Variants in Thailand and Identification of Hb A2-Walsgrave [codon 52 (GAT>CAT), Asp→His; HBD:c.157G>C] in a Pregnant Woman from Southern Thailand Genetic Testing and Molecular Biomarkers (IF1.795), Pub Date : 2021-06-16, DOI: 10.1089/gtmb.2020.0291 Thanet Prajantasen, Patcharawadee Prayalaw, Sitthichai Panyasai, Sukanya Binlee, Supang Nongnuan
Background: Delta-chain (δ-chain) variants are a group of rare hemoglobin (Hb) variants resulting from mutations within the δ-globin gene. Although quantification of Hb A2 levels is a useful screening tool for the beta-thalassemia trait, the coinheritance of a δ-globin gene mutation can lead to misinterpretation of diagnostic results.