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Bu3P-mediated acylation of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones with acyl chlorides
Chemistry of Heterocyclic Compounds  (IF1.277),  Pub Date : 2021-06-04, DOI: 10.1007/s10593-021-02939-x
Sha Li, Jiaxi Tan, Xiaofang Li

The (Z)-7-(1,2-diaryl-2-oxoethylidene)-6,7-dihydroindolizin-8(5H)-ones were synthesized in the acylation reaction of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones with acyl chlorides in the presence of Bu3P in moderate yields. The structures of all products were characterized thoroughly by NMR, IR, HRMS together with X-ray crystallographic analysis.