Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Whole-Exome Sequencing Identified DLG1 as a Candidate Gene for Familial Exudative Vitreoretinopathy Genetic Testing and Molecular Biomarkers (IF1.795), Pub Date : 2021-05-17, DOI: 10.1089/gtmb.2021.0013 Shanshan Zhang, Xiao Li, Wenjing Liu, Xiang Zhang, Lulin Huang, Shujin Li, Mu Yang, Peiquan Zhao, Jiyun Yang, Ping Fei, Xianjun Zhu, Zhenglin Yang
Purpose: Familial exudative vitreoretinopathy (FEVR) is a blinding retinal vascular disease. Clinically, FEVR is characterized by incomplete vascularization of the peripheral retina and pathological neovascularization. Only about 50% of FEVR cases can be explained by known FEVR disease gene variations. This study aimed to identify novel genes associated with the FEVR phenotype and explore their pathogenic mechanisms.