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Example:10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Hematocrit-Related Alterations of Circulating microRNA-21 Levels in Heart Failure Patients with Reduced Ejection Fraction: A Preliminary Study
Genetic Testing and Molecular Biomarkers  (IF1.795),  Pub Date : 2021-04-19, DOI: 10.1089/gtmb.2020.0277
Viera Nemcekova, Zuzana Kmecova, Lenka Bies Pivackova, Eva Goncalvesova, Peter Krenek, Gabriel Doka, Jan Klimas

Aim: Circulating microRNA-21 (miR-21) has been utilized as a diagnostic tool in the assessment of heart failure (HF). Blood constitution may be altered when HF occurs and miR-21 may affect hematopoiesis. Sample hemolysis may influence the determination of circulating miRNAs, challenging the diagnostic use of miRNAs.