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A review of combined treatments for melasma involving energy-based devices and proposed pathogenesis-oriented combinations
Journal of Cosmetic Dermatology  (IF2.696),  Pub Date : 2021-04-01, DOI: 10.1111/jocd.14110
Joseph N. Mehrabi, Efrat Bar-Ilan, Shehadeh Wasim, Amir Koren, Lior Zusmanovitch, Fares Salameh, Gila Isman Nelkenbaum, Tamir Horovitz, Eyal Zur, Ting Song Lim, Jacob Mashiah, Ofir Artzi

Melasma is an acquired disorder of hyperpigmentation, affecting a million individuals worldwide. Energy-based devices (EBDs) employed to treat melasma include various types of lasers, intense pulsed light (IPL), and radiofrequency (RF). Recent studies have attempted to address recalcitrant and recurring melasma by combining energy-based devices with topical or oral medications.