Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Construction of a microRNA–mRNA Regulatory Network in De Novo Cytogenetically Normal Acute Myeloid Leukemia Patients Genetic Testing and Molecular Biomarkers (IF1.795), Pub Date : 2021-03-17, DOI: 10.1089/gtmb.2020.0182 Ezalia Esa, Ariwibawa Kasmani Hashim, Elsa Haniffah Mejia Mohamed, Zubaidah Zakaria, Alifah Nadia Abu Hassan, Yuslina Mat Yusoff, Nor Rizan Kamaluddin, Ahmad Zuhairi Abdul Rahman, Kian-Meng Chang, Rashidah Mohamed, Indhira Subbiah, Ehram Jamian, Caroline Siew-Ling Ho, Soo-Min Lim, Peng-Choon Lau, Yuh-Fen Pung, Shamsul Mohd Zain
Background: The association between dysregulated microRNAs (miRNAs) and acute myeloid leukemia (AML) is well known. However, our understanding of the regulatory role of miRNAs in the cytogenetically normal AML (CN-AML) subtype pathway is still poor. The current study integrated miRNA and mRNA profiles to explore novel miRNA–mRNA interactions that affect the regulatory patterns of de novo CN-AML.