Example：10.1021/acsami.1c06204 or Chem. Rev., 2007, 107, 2411-2502
Current Status of COVID-19 Vaccine Development: Focusing on Antigen Design and Clinical Trials on Later Stages. Immune Network (IF6.303), Pub Date : 2021-02-26, DOI: 10.4110/in.2021.21.e4 Pureum Lee, Chang-Ung Kim, Sang Hawn Seo, Doo-Jin Kim
The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.