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Common and Uncommon Benign Pancreatic Lesions Mimicking Malignancy: Imaging Update and Review.
Seminars in Ultrasound, CT and MRI  (IF1.641),  Pub Date : 2018-03-25, DOI: 10.1053/j.sult.2017.10.002
Ulysses S Torres,Carlos Matsumoto,Augusto Cesar de Macedo Neto,Rogério Pedreschi Caldana,Ângela Hissae Motoyama Caiado,Dario Ariel Tiferes,Gisele Warmbrand,Laiz Laura de Godoy,Giuseppe D'Ippolito

There is a broad range of inflammatory, pseudotumoral, and benign lesions that may masquerade as pancreatic malignancies, often representing a challenge to the radiologist. Unawareness of these entities can lead to inadequate differential diagnoses or misdiagnosis, with important prognostic and therapeutic consequences. The purpose of this article is to revisit a spectrum of lesions, varying from common to exceedingly rare nonmalignant, that may mimic malignant pancreatic neoplasms on imaging, identifying relevant features that may contribute to reaching the correct diagnosis. Representative cases include focal fatty replacement, intrapancreatic accessory spleen, pancreatic lobulation, lipoma, autoimmune pancreatitis, focal pancreatitis, eosinophilic pancreatitis, groove pancreatitis, hemangioma, intrapancreatic aneurysm, tuberculosis, and Castleman's disease.